由于在纽约自然历史博物馆担任警卫有出色表现，拉瑞（本·斯蒂勒BenStiller饰）出任某家电小公司的CEO，而且还在电视上接受了著名脱口秀主持人的访谈，儿子对他仰慕，爱情如影随形，一派春风得意的样子不过，好景不长，当他故地重游，却意外发现馆长已经因为更新展览并准备把过时的展品挪到华盛顿的史密森博物馆继续展这让拉瑞感到有些气愤，他觉得自己有责任重振博物馆之雄风，于是他决定留下来再做一晚警卫，以唤起那些老朋友的共同努力。事实上，在搞定了罗斯福（罗宾·威廉斯RobinWilliams饰）、林肯、拿破仑、伊凡雷帝和阿尔•卡邦等人之后，他遭遇了一个劲敌——邪恶的古埃及法老的卡门拉，二人在夜晚再度上演了博物馆的惊魂对决……

The fantasy film "Night at the Museum 2" is also known as "Jurassic House 2", "Night at the Museum 2: Escape from the Smithsonian", etc. . Starring Ben Stiller, Amy Adams, Owen Wilson, Hank Azaria, and more, directed by Shawn Levy, written by Robert Ben Gallant and Thomas Lennon . It premiered in Washington on May 14, 2009, and was released in mainland China on May 26 of the same year. The film follows the comedy of the previous Night at the Museum 1 and continues to unfold the story in the museum. The museum guard Larry played by Ben Stiller has been very smooth since the end of Night at the Museum. He was promoted, and his relationship with his family became closer, and he even gained many admirers. However, when he returned to the museum again, he learned that the museum exhibits were going to be sent to the Smithsonian Museum in Washington for exhibition because they were outdated. He felt a little bit unwilling, so he decided to have another night at the Museum of Wonderful Night Tour